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AUBAGIO® (teriflunomide) is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

Do not take AUBAGIO if you have severe liver problems, are pregnant or of childbearing potential and not using effective birth control, have had an allergic reaction to AUBAGIO or leflunomide, or are taking a medicine called leflunomide for rheumatoid arthritis. View IMPORTANT SAFETY INFORMATION.

For U.S. residents only.

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No matter whether you just started your journey taking AUBAGIO® (teriflunomide) for relapsing MS or you’ve been taking it for a while, it’s always a good idea to remind yourself why staying with it as directed is an important strategy in your relapsing MS treatment plan.

On its face, it might seem “easy” to take AUBAGIO, right? It’s a once-daily pill that can be taken any time of day, with or without food.

But the reality is that taking any medication as prescribed – even a once daily pill – isn’t necessarily easy. In fact, taking medication as prescribed (also called adherence) is a complex behavior that can be influenced by lots of personal factors.

Take the quiz to test your knowledge about taking AUBAGIO as prescribed. And get helpful tips and pointers in this accompanying article

Yup or nope?

Taking medication as prescribed is important. Take this quiz to test your knowledge.

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Get tips for taking AUBAGIO

AUBAGIO is taken once daily, any time of day with or without food. But you should strive to take it at about the same time every day. It’s just a great way to establish a routine so you’re less likely to forget.

Here’s a tip to help. Pair taking AUBAGIO with another regular, daily activity such as brewing your first cup of coffee or brushing your teeth. That way, you’ll have a daily cue to remind you to take your medication. You can also add reminders to your smart phone or even use an app that can help with daily reminders.

Want more tips and hints about developing a routine? Check out this webpage.

Proven results of AUBAGIO

It’s helpful to remind yourself of why you and your doctor chose AUBAGIO to treat your relapsing MS.

It may also help to know that AUBAGIO was studied in three Phase III clinical trials.±

  • AUBAGIO 14 mg was shown to be effective vs placebo in 3 key measures: relapses, brain lesions, and disability progression.
    • AUBAGIO 14 mg and 7 mg achieved a significant relative risk reduction in relapse rate in Clinical Trial 1± (31%, 31%) and Clinical Trial 2± (36%, 22%) versus placebo.
    • AUBAGIO 14 mg and 7 mg significantly decreased the number of new lesions in Clinical Trial 1 (80%, 57%) versus placebo.
    • 80% of patients in Clinical Trial 1 and 84% of patients in Clinical Trial 2 remained free from disability progression with AUBAGIO 14 mg versus placebo (73% and 80%, respectively) over 108 weeks.
    • It could not be determined if AUBAGIO 7 mg was effective for disability progression
  • AUBAGIO also has a well-established history. This means AUBAGIO has 17+ years of ongoing clinical studies and real-world patient experience.

These may be some reasons why your doctor and you chose AUBAGIO to treat your relapsing MS.

If you have questions about why you were prescribed AUBAGIO as part of your treatment plan, be sure to ask questions to your care team. It can also help to reflect back to your doctor (in your own words) why you think you are taking the medication. Putting it into your own words may help reinforce your personal understanding of why it’s important to take treatment as prescribed.

It may also help to watch this webinar. It provides more in-depth information about AUBAGIO, including results from clinical studies and from patient experience, including effectiveness and possible side effects.

Do not take AUBAGIO if you

Have severe liver problems. AUBAGIO may cause serious liver problems, including liver failure that can be life-threatening and may require a liver transplant. Your risk may be higher if you already have liver problems or take other medicines that affect your liver. Your healthcare provider should do blood tests to check your liver within 6 months before you start AUBAGIO and monthly for 6 months after starting AUBAGIO. Tell your healthcare provider right away if you develop any of these symptoms of liver problems: nausea, vomiting, stomach pain, loss of appetite, tiredness, yellowing of your skin or whites of your eyes, or dark urine.

See more important safety information below.

Feeling informed about possible side effects

Every relapsing MS treatment is different, but each one comes with certain side effects. It is important to review the possible side effects of any medication you take.

AUBAGIO is processed by the liver. Your healthcare provider will test your liver enzymes before going on AUBAGIO and for the first 6 months on AUBAGIO to make sure you are tolerating treatment. Most people who had elevated liver enzymes during clinical trials returned to normal over time. Talk to your doctor about all the possible side effects associated with AUBAGIO.

You can learn more about possible side effects by reviewing important safety information below and by viewing resources we’ve collected for you.

View webpage

Getting support for access to AUBAGIO

If you or your doctor have any questions about your access to AUBAGIO, call MS One to One.

MS One to One can help you work through barriers to starting and staying on treatment with AUBAGIO.

Your dedicated MS One to One Nurse can help you:

  • research your insurance plan’s coverage of AUBAGIO
  • send a summary of benefits to your healthcare provider
  • make sense of your coverage

If your financial circumstances change and you are concerned about affording your treatment, MS One to One may be able to help. If you meet certain eligibility requirements, you may be able to get financial assistance to help pay for treatment.

MS One to One has nurses available 24/7. Call 1-855-676-6326.

You can also review some articles and videos about support available to you.

View webpage

IMPORTANT SAFETY INFORMATION

Do not take AUBAGIO if you have severe liver problems. AUBAGIO may cause serious liver problems, including liver failure that can be life-threatening and may require a liver transplant. View More

INDICATION

AUBAGIO® (teriflunomide) is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

IMPORTANT SAFETY INFORMATION

DO NOT TAKE AUBAGIO IF YOU:
  • Have severe liver problems. AUBAGIO may cause serious liver problems, including liver failure that can be life-threatening and may require a liver transplant. Your risk may be higher if you already have liver problems or take other medicines that affect your liver. Your healthcare provider should do blood tests to check your liver within 6 months before you start AUBAGIO and monthly for 6 months after starting AUBAGIO. Tell your healthcare provider right away if you develop any of these symptoms of liver problems: nausea, vomiting, stomach pain, loss of appetite, tiredness, yellowing of your skin or whites of your eyes, or dark urine.
  • Are pregnant. AUBAGIO may harm an unborn baby. You should have a pregnancy test before starting AUBAGIO. After stopping AUBAGIO, continue to use effective birth control until you have made sure your blood levels of AUBAGIO are lowered. If you become pregnant while taking AUBAGIO or within 2 years after stopping, tell your healthcare provider right away and enroll in the AUBAGIO Pregnancy Registry at 1-800-745-4447, option 2.
  • Are of childbearing potential and not using effective birth control.

    It is not known if AUBAGIO passes into breast milk. Your healthcare provider can help you decide if you should take AUBAGIO or breastfeed — you should not do both at the same time.

    If you are a man whose partner plans to become pregnant, you should stop taking AUBAGIO and talk with your healthcare provider about reducing the levels of AUBAGIO in your blood. If your partner does not plan to become pregnant, use effective birth control while taking AUBAGIO.

  • Have had an allergic reaction to AUBAGIO or a medicine called leflunomide.
  • Take a medicine called leflunomide for rheumatoid arthritis.

AUBAGIO may stay in your blood for up to 2 years after you stop taking it. Your healthcare provider can prescribe a medicine that can remove AUBAGIO from your blood quickly.

Before taking AUBAGIO, talk with your healthcare provider if you have: liver or kidney problems; a fever or infection, or if you are unable to fight infections; numbness or tingling in your hands or feet that is different from your MS symptoms; diabetes; serious skin problems when taking other medicines; breathing problems; or high blood pressure. Your healthcare provider will check your blood cell count and TB test before you start AUBAGIO. Talk with your healthcare provider if you take or are planning to take other medicines (especially medicines for treating cancer or controlling your immune system), over-the-counter medicines, vitamins or herbal supplements.

AUBAGIO may cause serious side effects. Tell your doctor if you have any of the following:

  • decreases in white blood cell count — this may cause you to have more infections. Symptoms include fever, tiredness, body aches, chills, nausea, or vomiting. Patients with low white blood cell count should not receive certain vaccinations during AUBAGIO treatment and 6 months after.
  • allergic reactions such as difficulty breathing, itching, or swelling on any part of your body including lips, eyes, throat, or tongue. Stop taking AUBAGIO and call your doctor right away.
  • serious skin reactions that may lead to death. Stop taking AUBAGIO if you have rash or redness and peeling, mouth sores or blisters.
  • other allergic reactions that may affect different parts of the body. If you have a fever or rash in combination with severe muscle pain, swollen lymph glands, swelling of your face, unusual bruising or bleeding, weakness or tiredness, or yellowing of your skin or the whites of your eyes, stop taking AUBAGIO and call your doctor right away.
  • numbness or tingling in your hands or feet that is different from your MS symptoms
  • high blood pressure
  • breathing problems (new or worsening) — these may be serious and lead to death

The most common side effects when taking AUBAGIO include: headache; diarrhea; nausea; hair thinning or loss; and abnormal liver test results. These are not all the side effects of AUBAGIO. Tell your healthcare provider about any side effect that bothers you.

Consult your healthcare provider if you have questions about your health or any medications you may be taking, including AUBAGIO.

Please click here for full Prescribing Information, including boxed WARNING and Medication Guide.